After the events of the previous game, the Kreisau Circle retrieves the critically injured William "B.J." Blazkowicz (Brian Bloom) from Deathshead's fortress before destroying it with a nuclear cannon. Blazkowicz falls into a 5-month long coma and has some of his organs removed to facilitate his survival. As Blazkowicz fades in and out during his coma aboard the Eva's Hammer (a stolen Nazi U-boat commandeered by the Kreisau Circle), it is revealed that Anya, Blazkowicz's love interest, is pregnant with twins. The U-boat is soon attacked by Frau Engel, a sadistic Nazi commander. Blazkowicz, disoriented and handicapped, fights his way to Anya and Set Roth, and the three proceed to the main deck. Soon after, however, Caroline is captured by Engel and her forces. Desperate to save his friends, Blazkowicz devises a plan to get himself captured and taken to Engel's airship, the Ausmerzer, which is suspending the U-boat above water. Frau Engel tries to get her overweight, abused daughter Sigrun to decapitate Caroline, but the former refuses, resulting in Engel killing Caroline herself. Sigrun then has a change of heart and tackles Engel, allowing Blazkowicz to use Caroline's armor to regain his strength. While Frau Engel escapes, Blazkowicz disconnects the Eva's Hammer from the Ausmerzer and flees back to the U-boat with Caroline's body.